Cart
sales@molnova.com
Home - Products - Others - Antioxidant - Mildronate dihydrate

Mildronate dihydrate

CAS No. 86426-17-7

Mildronate dihydrate( —— )

Catalog No. M19190 CAS No. 86426-17-7

Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 49 Get Quote
50MG 72 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Mildronate dihydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
  • Description
    Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
  • In Vitro
    RT-PCRCell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly decreased the mRNA expression of PFKP, PDK1, and PKM2 compared with the hypoxia group.Western Blot Analysis Cell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly reduced the protein expression of PFKP, PKM2, and LDHA.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    GBB hydroxylase
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    86426-17-7
  • Formula Weight
    147.19
  • Molecular Formula
    C6H14N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (548.79 mM)
  • SMILES
    C[N+](C)(C)NCCC(=O)[O-].O.O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Simkhovich BZ, et al. Biochem Pharmacol, 1988, 37(2), 195-202.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • L-Carnosine

    L-Carnosine is is an antioxidant naturally found in skeletal muscle brain tissue. It has the potential to suppress many of the biochemical changes that accompany aging.

  • 5,7-Dimethoxy-4-meth...

    5,7-Dimethoxy-4-methylcoumarin has potential antioxidant antiproliferative and anticancer or activity.

  • 5'-IMP disodium salt

    A flavor agent.

Sign In Join Free