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Mildronate dihydrate
CAS No. 86426-17-7
Mildronate dihydrate( —— )
Catalog No. M19190 CAS No. 86426-17-7
Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 49 | Get Quote |
|
| 50MG | 72 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMildronate dihydrate
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NoteResearch use only, not for human use.
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Brief DescriptionMildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
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DescriptionMildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
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In VitroRT-PCRCell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly decreased the mRNA expression of PFKP, PDK1, and PKM2 compared with the hypoxia group.Western Blot Analysis Cell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly reduced the protein expression of PFKP, PKM2, and LDHA.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetAntioxidant
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RecptorGBB hydroxylase
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number86426-17-7
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Formula Weight147.19
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Molecular FormulaC6H14N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (548.79 mM)
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SMILESC[N+](C)(C)NCCC(=O)[O-].O.O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Simkhovich BZ, et al. Biochem Pharmacol, 1988, 37(2), 195-202.
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