
Mildronate dihydrate
CAS No. 86426-17-7
Mildronate dihydrate( —— )
Catalog No. M19190 CAS No. 86426-17-7
Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
25MG | 49 | Get Quote |
![]() ![]() |
50MG | 72 | Get Quote |
![]() ![]() |
100MG | Get Quote | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameMildronate dihydrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionMildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
-
DescriptionMildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
-
In VitroRT-PCRCell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly decreased the mRNA expression of PFKP, PDK1, and PKM2 compared with the hypoxia group.Western Blot Analysis Cell Line:Rat alveolar type II epithelial RLE-6TN cells in hypoxia incubator Concentration:20, or 40 μM Incubation Time:24 h Result:Significantly reduced the protein expression of PFKP, PKM2, and LDHA.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetAntioxidant
-
RecptorGBB hydroxylase
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number86426-17-7
-
Formula Weight147.19
-
Molecular FormulaC6H14N2O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?H2O : 100 mg/mL (548.79 mM)
-
SMILESC[N+](C)(C)NCCC(=O)[O-].O.O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Simkhovich BZ, et al. Biochem Pharmacol, 1988, 37(2), 195-202.
molnova catalog



related products
-
Methyl-β-cyclodextri...
Methyl-β-cyclodextrin, a cyclic heptasaccharide, is an effective agent for the depletion of cholesterol from cells; also inhibits PEL cell growth with an IC50 of 3.33-4.23 mM.
-
Isatin
Isatin is an endogenous MAO inhibitor.
-
Procysteine
Procysteine is a precursor to glutathione (GSH) which is an important antioxidant in plants animals and fungi.